Are there histological changes in the liver due to NSAIDs?
The liver metabolizes many NSAIDs, and this can lead to histological changes in hepatic tissues. While most people tolerate NSAIDs well, some individuals may experience liver damage. This can manifest as hepatocellular injury, and in severe cases, lead to conditions such as hepatitis or even liver failure. Histologically, this might be observed as inflammation, necrosis, and fibrosis of liver cells.