How Do Histopathologists Identify Neoplastic Changes?
Neoplastic changes, or abnormal growths, can be benign or malignant. Histopathologists look for certain features to distinguish between them. Benign tumors typically have well-defined borders, uniform cell shapes, and low mitotic activity. In contrast, malignant tumors often exhibit irregular borders, cellular atypia, increased mitotic figures, and invasion into surrounding tissues. Immunohistochemistry, a technique that uses antibodies to detect specific antigens in the tissue, can further help in identifying the origin and type of the tumor.
