How Does Staining Help in Identifying Pathological Changes?
Staining is used to enhance the contrast in tissue sections, making different structures more visible under a microscope. Various staining techniques, such as Hematoxylin and Eosin (H&E) staining, highlight different tissue components. Hematoxylin stains the nuclei blue, while Eosin stains the cytoplasm and extracellular matrix pink. Special stains, like Periodic Acid-Schiff (PAS) and Masson's Trichrome, can be used to detect specific substances like glycogen and collagen, respectively, aiding in the diagnosis of certain conditions.
