Diagnosing infections histologically involves staining techniques and microscopic examination:
Hematoxylin and Eosin (H&E) Staining: This is the most common staining method used to identify general tissue architecture and the presence of inflammatory cells. Special Stains: Stains like Gram stain, Ziehl-Neelsen stain, and Periodic Acid-Schiff (PAS) are used to identify specific types of pathogens. Immunohistochemistry: This technique uses antibodies to detect specific antigens in tissues, helping to identify specific pathogens or immune responses.