Several factors can contribute to increased recurrence rates, particularly in cancer:
Incomplete Resection - If the initial surgical removal of a tumor is incomplete, residual cancer cells can lead to recurrence. Tumor Biology - Certain tumors have inherently aggressive biological characteristics that make them more likely to recur. Genetic Mutations - Mutations in specific genes can predispose cells to uncontrolled growth and recurrence. Microenvironment - The surrounding tissue environment can influence the likelihood of recurrence by supporting cancer cell survival and proliferation. Immune Response - A weakened immune system may be less effective at eliminating residual cancer cells.