What Are the Challenges in Studying CNVs in Histology?
There are several challenges in studying CNVs in histology. One major challenge is the heterogeneity of tissue samples, which can make it difficult to distinguish between normal and abnormal cells. Another challenge is the technical limitations of current detection methods, which may not always provide the resolution needed to identify small or complex CNVs. Additionally, interpreting the functional significance of detected CNVs requires a deep understanding of the underlying biology and the context in which they occur.