Why is the Human Cell Atlas Important in Histology?
Histology is the study of the microscopic structure of tissues. Traditionally, histological studies have relied on techniques such as light microscopy and staining to observe cells within tissues. However, these methods have limitations in identifying and characterizing the diverse cell types present in complex tissues. The HCA leverages advanced technologies like single-cell RNA sequencing and spatial transcriptomics to provide a more detailed and comprehensive view of tissue architecture, enabling histologists to identify and study different cell types with unprecedented precision.