What is the Relevance of Immunohistochemistry in Assessing Tissue Injury?
Immunohistochemistry (IHC) is crucial for assessing tissue injury as it allows for the detection of specific proteins associated with cellular responses. For example, IHC can identify markers of cell proliferation (e.g., Ki-67), apoptosis (e.g., caspase-3), and inflammation (e.g., CD45 for leukocytes). This technique provides insights into the molecular mechanisms underlying tissue injury and repair.