In histology, the Akt pathway's significance is underscored by its involvement in tissue development, repair, and homeostasis. For example, in muscle tissue, Akt activation leads to increased protein synthesis and muscle hypertrophy. In adipose tissue, it influences lipid metabolism and storage. Additionally, the pathway is vital in epithelial cells for wound healing and regeneration. Dysregulation of the Akt pathway is often observed in various pathological conditions, including cancer, where it contributes to uncontrolled cell proliferation and resistance to apoptosis.
