What are the Clinical Implications of the Akt Pathway?
Given its central role in cell survival and growth, the Akt pathway is a critical target for therapeutic interventions in diseases like cancer, diabetes, and cardiovascular disorders. In cancer, inhibitors of PI3K, Akt, and mTOR are being developed and tested in clinical trials. In diabetes, modulating Akt activity can improve insulin sensitivity and glucose homeostasis. Understanding the Akt pathway's regulation and function in various tissues aids in the development of targeted therapies, highlighting its importance in both basic research and clinical applications.
