Why is reproducibility a challenge in histological studies?
Reproducibility is a major challenge in histological studies due to several factors:
1. Variability in Sample Preparation: Differences in fixation, embedding, and sectioning techniques can lead to variability in tissue morphology and staining. 2. Inter-Observer Variability: Different observers might interpret the same histological features differently, affecting reproducibility. 3. Instrument Calibration: Variability in microscope settings and image capture parameters can introduce inconsistencies.
