What Therapeutic Approaches Target Interleukin 1 Receptors?
Several therapeutic approaches aim to modulate IL-1R signaling to treat inflammatory diseases. These include IL-1R antagonists like Anakinra, which block IL-1 from binding to IL-1R1, and monoclonal antibodies such as Canakinumab, which neutralize IL-1 itself. These therapies can reduce inflammation and alleviate symptoms in conditions driven by excessive IL-1R signaling.