Interleukin 1 receptors (IL-1Rs) are a group of receptors that bind to interleukin 1 (IL-1), a crucial cytokine in the immune system. IL-1 plays a critical role in the response to injuries and infections, mediating inflammation and immune responses. The IL-1 receptor family is composed of several members, including IL-1R1 and IL-1R2, which have distinct but overlapping functions.