Proteomic studies in histology often utilize a combination of advanced technologies. Key technologies include mass spectrometry, which allows for the precise identification and quantification of proteins. Additionally, two-dimensional gel electrophoresis (2-DE) is used to separate proteins based on their isoelectric point and molecular weight. Techniques such as liquid chromatography (LC) and tandem mass spectrometry (MS/MS) provide high-resolution analysis of protein mixtures.