The release of zymogen granules is typically stimulated by hormonal and neural signals. For instance, the hormone cholecystokinin (CCK) stimulates the pancreas to release its zymogen granules. Similarly, the sight, smell, or taste of food can trigger neural pathways that result in the secretion of these granules. This regulated release ensures that digestive enzymes are available precisely when needed, preventing unnecessary enzyme activity that could damage tissues.
