What is the Clinical Significance of Zymogen Granules?
Zymogen granules are crucial for normal digestive function. Disorders in the formation or release of these granules can lead to digestive diseases. For example, in chronic pancreatitis, the acinar cells may lose their ability to produce or secrete zymogen granules, leading to malabsorption and nutritional deficiencies. Understanding the biology of zymogen granules can help in diagnosing and developing treatments for such conditions.