The primary effect of LPS on tissues is the induction of an inflammatory response. This occurs because LPS binds to Toll-like receptor 4 (TLR4) on the surface of immune cells, activating them and leading to the release of cytokines. These cytokines cause blood vessels to become more permeable, allowing immune cells to enter the tissue and combat the infection. However, excessive LPS can lead to a condition known as septic shock, characterized by widespread inflammation and tissue damage.
