What Role Do Glial Cells Play in Neurodegeneration?
Glial cells, including astrocytes, microglia, and oligodendrocytes, play a significant role in neurodegeneration. Gliosis, a reactive change in glial cells, is a common response to neuronal injury. Microglia can become activated and release inflammatory cytokines, contributing to neuroinflammation, which exacerbates neuronal damage.