What is the significance of NHE1 in cellular function?
NHE1 plays a vital role in several cellular processes:
Regulation of pH: By exchanging intracellular H+ for extracellular Na+, NHE1 helps to maintain the acid-base balance within cells. Cell Volume Regulation: It contributes to the control of cell volume by modulating ion concentrations and osmotic balance. Cell Proliferation and Differentiation: NHE1 activity is linked to cell growth and differentiation, making it essential for tissue development and repair.