complement receptors (crs)

What is the Role of Complement Receptors in Disease?


Dysfunction or overactivation of complement receptors can lead to a variety of autoimmune diseases and inflammatory conditions. For example, deficiencies in CR1 may result in inefficient clearance of immune complexes, contributing to diseases such as systemic lupus erythematosus. Furthermore, overactivation of CR3 and CR4 has been implicated in chronic inflammatory diseases like rheumatoid arthritis.

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