Complement receptors function by binding to complement-coated pathogens or immune complexes. This binding triggers a cascade of cellular responses:
Opsonization: CRs enhance the ability of phagocytes to engulf and destroy pathogens. Inflammatory Response: Activation of CRs on immune cells can lead to the release of inflammatory cytokines and chemokines, recruiting more immune cells to the site of infection. Clearance of Immune Complexes: CRs help in the removal of circulating immune complexes, preventing their deposition in tissues which could lead to inflammation.
