What is the Impact of KRAS Mutations on Cellular Histology?
KRAS mutations often result in histological changes within the affected tissues. These changes can include increased cellular proliferation, altered tissue architecture, and the presence of atypical or dysplastic cells. In cancers such as colorectal carcinoma, pancreatic ductal adenocarcinoma, and non-small cell lung cancer, these mutations are frequently observed and are associated with poor prognosis.