In endothelial cells, VASP is instrumental in modulating cell shape and motility. These cells line blood vessels and are crucial for maintaining vascular integrity and function. VASP promotes the formation of cell-cell junctions and supports endothelial barrier function, thereby preventing excessive permeability and maintaining vascular homeostasis. Additionally, VASP facilitates the repair of endothelial monolayers after injury, contributing to vascular healing processes.
