What are the Challenges in Studying KRAS Mutations in Histology?
One of the main challenges in studying KRAS mutations in histology is the heterogeneity of tumors. Different regions of a tumor may harbor different genetic mutations, making it difficult to obtain a comprehensive understanding of the mutation landscape. Additionally, the small size of biopsy samples can limit the amount of genetic material available for analysis. Advances in molecular pathology and the development of more sensitive detection methods are helping to address these challenges.
