What is the Histological Significance of Xanthine Oxidase?
The presence and activity of xanthine oxidase in tissues are significant for several reasons. It plays a role in the cellular redox state by producing reactive oxygen species (ROS) during the oxidation process. Excessive activity of xanthine oxidase can lead to oxidative stress, which has been implicated in various pathological conditions such as ischemia-reperfusion injury, cardiovascular diseases, and chronic inflammatory states.