How is Xanthine Oxidase Detected in Histological Samples?
Detection of xanthine oxidase in histological samples can be performed using several techniques. Immunohistochemistry (IHC) is a common method, which involves using antibodies specific to xanthine oxidase to visualize its distribution within tissues. This technique provides spatial context to the enzyme’s localization. Additionally, enzyme histochemistry can be employed to detect its activity by using substrates that produce a colorimetric change upon oxidation by xanthine oxidase.
