The Cockcroft-Gault equation is a formula that estimates the creatinine clearance from serum creatinine levels, age, body weight, and sex. The equation is: CrCl = [(140 - age) × weight (kg)] / [72 × serum creatinine (mg/dL)] (for males) For females, the result is multiplied by 0.85 to account for generally lower muscle mass.