What is the Clinical Significance of Secretory IgA?
sIgA plays a vital role in protecting against respiratory and gastrointestinal infections. Deficiencies in sIgA production can lead to increased susceptibility to infections and autoimmune diseases. Measuring sIgA levels can help diagnose certain immunodeficiency disorders and assess mucosal immune function. Moreover, sIgA has become an area of interest in vaccine development, particularly mucosal vaccines, aiming to enhance protective immunity at mucosal surfaces.
