What is the Role of Secretory IgA in the Immune System?
sIgA serves as a first line of defense by neutralizing pathogens and toxins, preventing their attachment and invasion of epithelial cells. It functions in immune exclusion by binding to antigens and entrapping them in mucus, facilitating their removal from the body. Additionally, sIgA plays a role in immune regulation by interacting with commensal microorganisms and maintaining mucosal homeostasis. By doing so, it contributes to the prevention of inflammatory responses that could damage mucosal tissues.
