Can Secretory IgA Be Influenced by External Factors?
Yes, several factors can influence the levels and function of sIgA. Stress, diet, and exercise have been shown to affect sIgA secretion. Chronic stress can lead to reduced sIgA levels, thereby compromising mucosal immunity. Conversely, moderate physical activity is associated with increased sIgA secretion, promoting better immune protection. Nutritional factors, such as vitamin A and probiotics, can also modulate sIgA production and function, highlighting the interplay between lifestyle factors and mucosal immunity.