What is the Clinical Significance of Lipid Inclusions?
Lipid inclusions can be indicative of various metabolic and pathological conditions. For example, excessive lipid accumulation in hepatocytes is a hallmark of steatosis (fatty liver disease), which can result from alcohol abuse, obesity, or metabolic syndrome. In adrenal glands, lipid inclusions are essential for the synthesis of steroid hormones. Abnormalities in lipid storage can also be seen in lysosomal storage diseases such as Niemann-Pick disease.
