What is the Clinical Significance of Double-Stranded DNA?
Abnormalities in dsDNA, such as mutations, can lead to a variety of diseases, including cancer. In histopathology, the study of diseased tissues, examining the structure and integrity of dsDNA can aid in the diagnosis of genetic disorders and malignancies. Techniques such as polymerase chain reaction (PCR) and next-generation sequencing are employed to analyze DNA from tissue samples, providing valuable information for clinical decision-making.