Double-stranded DNA (dsDNA) is the fundamental genetic material found in the cells of most living organisms, including humans. It consists of two complementary strands that coil around each other to form a double helix. This structure is stabilized by hydrogen bonds between the nucleotide bases: adenine with thymine and cytosine with guanine. The double helix model was first described by James Watson and Francis Crick in 1953, building on the work of Rosalind Franklin and others.