What is Synaptic Plasticity and How Is TrkB Involved?
Synaptic plasticity refers to the ability of synapses to strengthen or weaken over time, which is fundamental to learning and memory. TrkB activation by BDNF enhances synaptic strength by increasing the number of synaptic vesicles, receptors, and signaling molecules at the synapse. This process is crucial for long-term potentiation (LTP), a cellular mechanism underlying learning and memory.
