The TrkB receptor, also known as Tropomyosin receptor kinase B, is a member of the receptor tyrosine kinase family. It is encoded by the NTRK2 gene and is primarily involved in the signaling pathways that regulate neuronal survival, development, and synaptic plasticity. The TrkB receptor is activated by binding to neurotrophins such as Brain-Derived Neurotrophic Factor (BDNF), Neurotrophin-4 (NT-4), and Neurotrophin-3 (NT-3).