What is Senescence Associated β Galactosidase (SA β Gal)?
Senescence associated β galactosidase (SA β Gal) is an enzyme that is commonly used as a biomarker for cellular senescence. Cellular senescence refers to the irreversible arrest of cell division that occurs in response to various stressors. SA β Gal activity is typically detected at pH 6, a feature that distinguishes it from other β galactosidases which are active at more acidic pH levels.