How Does Biological Variability Affect Histological Analysis?

Biological variability is inherent and can be attributed to the natural differences between individuals. For instance, age-related changes can influence the appearance of tissues, as seen in the thickening of arterial walls in older adults. Similarly, sex-based differences can affect tissues, like the differences in muscle fiber composition between males and females. Genetic factors also play a role, where certain genetic mutations can lead to histological changes observed in diseases.