senescence associated β galactosidase (sa β gal)

What Are the Applications of SA β Gal Staining?

SA β Gal staining is widely used in various fields of biological research:
1. Aging Research: By identifying senescent cells in tissues, researchers can study the role of cellular senescence in the aging process and age-related diseases.
2. Cancer Research: SA β Gal staining helps in understanding the tumor microenvironment, as senescent cells can influence tumor progression and response to therapy.
3. Drug Development: Evaluating the efficacy of senolytic drugs, which are designed to eliminate senescent cells, often involves SA β Gal staining to quantify the reduction of these cells in treated tissues.

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