Chronic myelomonocytic leukemia (CMML) is a type of hematologic malignancy that exhibits features of both myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPNs). It primarily affects the bone marrow and blood, leading to an overproduction of monocytes and immature white blood cells. CMML is considered a clonal disorder of the hematopoietic stem cell, characterized by persistent monocytosis.
