What Histological Techniques are Used to Study Pathological Angiogenesis?
Several histological techniques are employed to study pathological angiogenesis. Immunohistochemistry (IHC) is commonly used to detect specific proteins involved in angiogenesis within tissue sections. In situ hybridization can be used to localize specific mRNA transcripts. Additionally, microvessel density (MVD) is often assessed as a measure of angiogenesis, using markers like CD31 or CD34 to stain endothelial cells.
