What Histological Techniques are Used to Study Chemopreventive Agents?
Several histological techniques are employed to investigate the effects of chemopreventive agents, including:
Hematoxylin and Eosin (H&E) staining: A standard technique to observe general tissue architecture and cell morphology. Immunohistochemistry (IHC): Used to detect specific proteins and markers related to cell proliferation, apoptosis, and other cellular processes. TUNEL assay: A method for detecting DNA fragmentation indicative of apoptosis. Electron microscopy: Provides detailed images of cellular and subcellular structures.
