Several methods can be used to remove mercury pigment from tissue sections:
- Iodine and Sodium Thiosulfate Treatment: One common technique involves treating the tissue sections with an iodine solution followed by sodium thiosulfate. The iodine reacts with the mercury deposits, forming mercuric iodide, which is then dissolved by the sodium thiosulfate. - Physical Removal: In some cases, gentle brushing or scraping of the tissue sections can help remove the pigment deposits. - Alternative Fixatives: Using non-mercury fixatives can prevent the formation of mercury pigments altogether. Alternatives like formalin or Bouin's solution can be used depending on the tissue type and the required quality of preservation.
