What Histological Changes are Indicative of Bacterial Infections?
Bacterial infections can cause a variety of histological changes, including: - Inflammation: The presence of neutrophils, macrophages, and other inflammatory cells is a hallmark of bacterial infections. Acute infections often show a predominance of neutrophils, while chronic infections may involve more macrophages and lymphocytes. - Necrosis: Bacterial toxins can cause cell death, leading to areas of tissue necrosis. - Granuloma Formation: Chronic bacterial infections, such as tuberculosis, can lead to the formation of granulomas, which are organized collections of macrophages, often surrounded by lymphocytes. - Abscess Formation: Pus-filled cavities known as abscesses may form as a result of severe bacterial infections.
