What are the Limitations of Histological Examination in Bacterial Infections?
While histological examination is a powerful tool, it has its limitations: - Sensitivity: Some bacterial infections may be difficult to detect if the bacterial load is low or if the organisms are not well-preserved in the tissue sample. - Specificity: Certain histological changes, such as inflammation, can be caused by various infectious and non-infectious agents, making it challenging to pinpoint the exact cause without additional tests. - Time-Consuming: Preparing and analyzing tissue samples can be time-consuming, which may delay the diagnosis and treatment of acute infections.
