Several factors contribute to tissue degradation in histology: - Environmental Conditions: Exposure to air, light, and fluctuating temperatures can accelerate tissue degradation. - Improper Handling: Rough handling during dissection or transfer can cause mechanical damage to tissues. - Delayed Fixation: The longer the delay before fixation, the higher the likelihood of autolysis and bacterial growth. - Chemical Reactivity: Inadequate or improper use of fixatives can lead to partial degradation or chemical alterations of the tissue.
