Axonal damage can be caused by several factors including:
Physical Trauma: Injury from accidents, falls, or sports can lead to axonal shearing. Ischemia: Reduced blood flow to the brain or spinal cord can deprive neurons of oxygen, leading to axonal injury. Neurodegenerative Diseases: Conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis can cause progressive axonal damage. Toxins and Chemicals: Exposure to certain toxic substances can result in axonal degeneration.
