What are the Histological Features of Axonal Damage?
Histological examination of axonal damage reveals several characteristic features:
Axonal Swelling: Damaged axons often exhibit swelling and the formation of axonal bulbs. Fragmentation: Axons may undergo fragmentation and the formation of retraction balls. Myelin Sheath Degeneration: The protective myelin sheath around axons may break down. Accumulation of Organelles: Damaged axons often show an accumulation of organelles such as mitochondria and lysosomes.
