Axonal damage can lead to significant neurological deficits. The consequences depend on the location and extent of the damage:
Motor Impairments: Damage to motor neurons can result in muscle weakness, paralysis, or spasticity. Sensory Deficits: Injury to sensory neurons can cause loss of sensation, numbness, or neuropathic pain. Cognitive Dysfunction: In conditions like Alzheimer's disease, axonal damage is associated with memory loss and cognitive decline. Autonomic Dysfunction: Damage to autonomic nerves can affect heart rate, blood pressure, and gastrointestinal function.