mature tgf β

What are the Therapeutic Implications of Targeting TGF-β?

Given its involvement in various diseases, targeting TGF-β signaling presents promising therapeutic opportunities:
1. Cancer Therapy: Inhibitors of TGF-β or its receptors are being explored as potential treatments to prevent tumor progression and metastasis.
2. Anti-fibrotic Agents: Drugs that block TGF-β activity are under investigation for treating fibrotic diseases by reducing ECM production and deposition.
3. Immune Modulation: Modulating TGF-β signaling could offer new strategies for treating autoimmune diseases and enhancing immune tolerance.

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