What are the Research Implications of TDP-43 in Histology?
The study of TDP-43 in histology has substantial research implications. Understanding the mechanisms of TDP-43 aggregation and its role in neuronal death can lead to the development of therapeutic strategies. Research is ongoing to discover ways to prevent TDP-43 misfolding and to clear existing aggregates, which could provide treatments for ALS, FTLD, and other related disorders.